| Instructor(s) | Dr. Owais Khan [Coordinator] Office: ENG328 Phone: (416) 979-5000 x 556096 Email: owaiskhan@torontomu.ca Office Hours: | ||||||||||||
| Calendar Description | Tissue engineering approach for augmentation or replacement of compromised tissue function in nerve, microvessels, skin and cartilage. Integrative exploration of the use of three-dimensional polymeric scaffolds and drug delivery vehicles, and gene therapy and cellular engineering for functional repair of injured tissues. | ||||||||||||
| Prerequisites | BLG 601 and BLG 701 | ||||||||||||
| Antirequisites | None | ||||||||||||
| Corerequisites | None | ||||||||||||
| Compulsory Text(s): |
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| Reference Text(s): |
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| Learning Objectives (Indicators) | At the end of this course, the successful student will be able to:
NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB). | ||||||||||||
| Course Organization | 3.0 hours of lecture per week for 13 weeks | ||||||||||||
| Teaching Assistants | Lab Teaching Assistants ----------------------- Ryan Phillip Mcneice (rmcneice@torontomu.ca) Kiarash (Kia) Alizadeh (kalizadeh@torontomu.ca) Tutorial Teaching Assistants ---------------------------- Malak Abdalmaksoud (malak.abdalmaksoud@torontomu.ca) Ajay Singh (ajay.banwait.singh@torontomu.ca ) | ||||||||||||
| Course Evaluation |
Note: In order for a student to pass a course, a minimum overall course mark of 50% must be obtained. In addition, for courses that have both "Theory and Laboratory" components, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section above for details on the Theory and Laboratory components (if applicable). | ||||||||||||
| Examinations | Midterm exam in Week 7, two hours (covers Weeks 1-6) Final exam, during exam period, three hours (covers Weeks 1-13). | ||||||||||||
| Other Evaluation Information | Important Notes: =============== Any late submission of laboratory report (without justifiable reasons and advanced notice to the instructor/TA) will result in a mark deduction as below: a. A zero mark will be awarded for handing in no lab report b. 10% deduction if submitted within 24 hours late c. 20% deduction per day past deadline | ||||||||||||
| Teaching Methods | Email Policy ============ In accordance with the Policy on Student E-mail Accounts (Policy 157), Toronto Metropolitan University (TMU) requires that any electronic communication by students to TMU faculty or staff be sent from their official university email account. Teaching Methods ================ Please refer to BME 703 Tissue Engineering Laboratory Manual for additional details of each lab session. All lab reports must have the standard cover page, to be signed by the student prior to submission, which can be completed and printed from the Department website at: https://www.ecb.torontomu.ca/guides/Standard_Cover_Page_Assignments.pdf | ||||||||||||
| Other Information | None | ||||||||||||
Week | Hours | Chapters / | Topic, description |
|---|---|---|---|
1 | 3 | Notes | Introduction to Tissue Engineering |
2 | 3 | Chapter 1 Sections 1.1-1.3 and Notes | Cellular Therapies |
3 | 3 | Chapter 2 Sections 2.1-2.3 and Notes | Tissue Organization |
4 | 3 | Chapter 5 and Notes | Stem Cells |
5 | 3 | Chapter 3, 4 and Notes | Tissue Dynamics and Morphogenesis |
6 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cell Differentiation |
7 | 3 | Midterm | ------------- MIDTERM EXAM------------- |
8 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cellular Fate Processes I |
9 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cellular Fate Process II |
10 | 3 | Chapter 10 and Notes | Cell and Tissue Culture |
11 | 3 | Chapter 13 and Notes | Scaling up for Ex-Vivo Cultivation |
12 | 3 | Notes | Ethics, IP and Regulatory Affairs |
13 | 3 | Notes | Review |
Week | L/T/A | Description |
|---|---|---|
2 | Tutorial 1 | Tutorial 1 |
3 | Lab 1 Modules | Lab Safety; Biosafety; Pipetting; Microscopy |
4 | Tutorial 2 | Tutorial 2 |
5 | Lab 2 Modules | Membranes |
6 | Tutorial 3 | Tutorial 3 |
7 | Lab 3 Modules | Cytoskeleton |
8 | Tutorial 4 | Tutorial 4 |
9 | Lab 4 Modules | Phagocytosis |
10 | Tutorial 5 | Tutorial 5 |
11 | Lab 5 Modules | Growth of Cells |
Students are reminded that they are required to adhere to all relevant university policies found in their online course shell in D2L and/or on the Senate website
Refer to the Departmental FAQ page for furhter information on common questions.
The University Libraries provide research workshops and individual consultation appointments. There is a drop-in Research Help desk on the second floor of the library, and students can use the Library's virtual research help service to speak with a librarian, or book an appointment to meet in person or online.
You can submit an Academic Consideration Request when an extenuating circumstance has occurred that has significantly impacted your ability to fulfill an academic requirement. You may always visit the Senate website and select the blue radio button on the top right hand side entitled: Academic Consideration Request (ACR) to submit this request.
For Extenuating Circumstances, Policy 167: Academic Consideration allows for a once per semester ACR request without supporting documentation if the absence is less than 3 days in duration and is not for a final exam/final assessment. Absences more than 3 days in duration and those that involve a final exam/final assessment, always require documentation. Students must notify their faculty/contract lecturer once a request for academic consideration is submitted. See Senate Policy 167: Academic Consideration.
Longer absences are not addressed through Policy 167 and should be discussed with your Chair/Director/Program to be advised on next steps.
Visit the Electrical, Computer and, Biomedical Engineering department's faculty page for contact information.
Students are to strictly adhere and follow:
During the lab sessions, to avoid tripping hazards, the area around the lab stations should not be surrounded by bags, backpacks etc, students should place their bags, backpacks etc against the walls of the labs and/or away from their lab stations in such a way that it avoids tripping hazards.
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Academic Accommodation Support (AAS) is the university's accessibility services office, supporting students with disabilities. AAS works with students, faculty, and staff to create inclusive learning environments, reduce barriers, and promote accessibility across the university.
If you have (or suspect you may have) a disability, AAS can provide consultation, guide you through registration, develop accommodation plans where appropriate, and connect you with supports and services. For information about eligibility, documentation requirements, registration, deadlines, and available services, visit AAS.
Academic Accommodations (for students with disabilities) and Academic Consideration (for short-term extenuating circumstances) are governed by different university policies. Learn more about each process and how to access support. Students registered with AAS may request academic consideration (related or unrelated to their disability) if they experience extenuating circumstances that impact their ability to meet their shorter term academic obligations. This includes short term physical or mental health issues that are sudden/acute (e.g, the flu), unexpected illness or injury, hospitalization or treatment, and significant aggravation of a pre-existing condition. Please see Policy 167: Academic Consideration for more information and details.
Please note that there is no accommodation for missing/rescheduling or reweighting of tests - this is considered an alternate arrangement. Any student who misses a test/exam will be directed to submit an ACR to explore if possible alternate arrangements under Policy 167: Academic Consideration can apply .
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We encourage all Toronto Metropolitan University community members to access available resources to ensure support is reachable. You can find more resources available through the Toronto Metropolitan University Wellbeing Central website.